Quick Guide: Parent Advice Sheet

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Parent Advice Sheet – Commonly observed adverse events following immunisation and what to do about them
 

The following information can be photocopied and given to parents as post-vaccination advice.

All the common adverse events following immunisation are usually mild and transient and treatment is not usually required. If the adverse event following immunisation is severe or persistent, or if you are worried about yourself or your child’s condition, see your doctor or immunisation clinic nurse as soon as possible or go to a hospital.

Commonly observed adverse events (conditions) following specific vaccines used in the Australian Standard Vaccination Schedule (ASVS)

VZV MMR MenCCV
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)

Seen 5-26 days after vaccination:

  • Pustular rash (2-5 lesions) usually at injection site which occasional covers other parts of the body
  • Occasionally injection site nodule – may last many weeks (no treatment needed)

Seen 7 to 10 days after vaccination:

  • Low grade temperature (fever) lasting 2-3 days, faint red rash (not infectious), head cold and/or runny nose, cough and/or puffy eyes
  • Drowsiness or tiredness
  • Swelling of salivary glands
  • Irritable, crying, unsettled and generally unhappy
  • Loss of appetite
  • Headache (usually observed in adolescent/adults)
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
DTPa-containing vaccines & dTpa Influenza IPV & IPV-containing vaccines
  • Irritable, crying, unsettled and generally unhappy
  • Drowsiness or tiredness
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
  • Drowsiness or tiredness
  • Muscle aches
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
  • Muscle aches
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
HepB Hib 23vPPV
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)
7vPCV OPV dT (ADT)
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Occasional diarrhoea (no treatment usually needed but parent or carer must wash hands carefully after changing nappies)
  • Localized pain, redness & swelling at injection site
  • Occasionally injection site nodule – may last many weeks (no treatment needed)
  • Low grade temperature (fever)

 

Key to table:
DTPa Diphtheria-tetanus-pertussis (acellular) infant/child formulation
dTpa Adult/adolescent formulation diphtheria-tetanus-pertussis (acellular) vaccine
dT or ADT Adult diphtheria-tetanus vaccine
hepB hepatitis B vaccine
Hib Haemophilus influenzae type b (Hib) vaccine PRP-OMP, PRP-T, HbOC (as monovalent or in combination)
Influenza Influenza vaccine
IPV Inactivated poliomyelitis vaccine (usually in combination with other vaccine and given as injection)
7vPCV 7-valent pneumococcal conjugate vaccine
23vPPV 23-valent pneumococcal polysaccharide vaccine
MenCCV Meningococcal C conjugate vaccine
MMR measles-mumps-rubella vaccine
OPV oral poliomyelitis vaccine
VZV varicella-zoster vaccine (both Varivax Refrigerated and Varilrix, unless stated otherwise)
NA not applicable

What to do to manage injection site discomfort
 

Many vaccine injections may result in soreness, redness, itching, swelling or burning at the injection site for 1 to 2 days. Paracetamol might be required to ease the discomfort. Sometimes a small, hard lump may persist for some weeks or months. This should not be of concern and requires no treatment.

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Managing fever after immunisation
 

Give extra fluids to drink. Do not overdress the baby if hot. Although the routine use of paracetamol at the time of vaccination is no longer necessary, it may be required if, for example, an infant or child has a high fever following vaccination. The dose of paracetamol is 15 mg/kg of paracetamol liquid, up to a maximum daily dose of 90 mg/kg/day.

Reference: see Part 1.6, ‘Adverse events following immunisation (AEFI)’ for more information.

 

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